The Prism Program
The TCP panel
The TCP (tumour control probability) panel consists of two regions. In the top area the parameters required for the TCP model can be entered and modified.
These parameters are:
| α0 | Parameter referring to the linear term in the linear quadratic model (compare to literature, see Further reading) |
| β0 | Parameter referring to the quadratic term in the linear quadratic model |
| ρ | Uniform density of clonogenic cells in tumour |
| σ |
Standard deviation of a Gaussian distribution of the mean α0 (to incorporate patient heterogeneity)
|
| Patients | Number of patients with varying α0 |
| Teff | Effective doubling time of tumour clonogens (in days) |
| Ttotal | Overall treatment time (in days) |
| TK | Time between first treatment and the start of tumour proliferation (in days) |
In
the bottom
half of the panel all plans selected in the DVH panel are listed in
combination with the readout for the TCP value.
Functions of the different elements:
-
Help: Opens a panel containing information about the TCP panel
-
Read Param: Retrieve set of parameters.
-
Write Param: Store set of parameters.
-
Calc: When pressing this button the tumour control probability is calculated with the parameters specified on top and for the selected plans, which are listed above.
For further information about the TCP and the NTCP panel: see Prism User’s Reference Manual, p. 75ff.
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